1. We recommend multidisciplinary comprehensive smoking cessation interventions for patients with asymptomatic PAD who use tobacco (repeatedly until tobacco use has stopped) (Grade 1, Level A).
2. We recommend providing education about the signs and symptoms of PAD progression to asymptomatic patients with PAD (Grade 1, Level Ungraded).
3. We recommend against invasive treatments for PAD in the absence of symptoms, regardless of hemodynamic measures or imaging findings demonstrating PAD (Grade 1, Level B).

PAD, peripheral arterial disease.