| Strength of a recommendation |
|---|
| Strong |
| Benefits > Risks |
| Risks > Benefits |
| Weak |
| Benefits ~ Risks |
| Quality of evidence precludes accurate assessment of risks and benefits |
| Grading quality of evidence |
| High |
| Additional research is considered very unlikely to change confidence in the estimate of effect |
| Moderate |
| Further research is likely to have an important impact on in the estimate of effect |
| Low |
| Further research is very likely to change the estimate of the effect |
Adapted from Guyatt G, Gutterman D, Baumann MH, Addrizzo-Harris D, Hylek EM, Phillips B, et al. Grading strength of recommendations and quality of evidence in clinical guidelines. Chest 2006;129:174-81.