β-Blocker Therapy Recommendations
- All CABG patients should be prescribed perioperative β-blocker therapy to prevent postoperative AF, ideally starting before surgery, unless contraindicated (ie, bradycardia, severe reactive airway disease) (Class I; Level of Evidence A).
- CABG patients with a history of MI should be prescribed β-blocker therapy unless contraindicated (Class I; Level of Evidence A).
- CABG patients with LV dysfunction should be prescribed β-blocker therapy (bisoprolol, sustainedrelease metoprolol succinate, or carvedilol), unless contraindicated (Class I; Level of Evidence B).
- Chronic β-blocker therapy for hypertension treatment after CABG (in the absence of prior MI or LV dysfunction) may be considered, but other antihypertensive therapies may be more effective and more easily tolerated (Class IIb; Level of Evidence B).