The echocardiographic assessment of mitral functional anatomy and the determination of the mechanism of MR are mandatory to select patients who can benefit from percutaneous intervention and to tailor the repair strategy. Both degenerative and functional/ischemic MR can be suitable for percutaneous valve repair through a variety of approaches including those that offer direct leaflet repair, direct or indirect annular remodeling and ventricular remodeling.

Table 3 summarizes the clinical experience with available devices for percutaneous mitral valve repair.