Proposed imaging methods and follow-up intervals in in family members (mutation positive or first degree relatives from families without identified mutations)

Family members from approximately 10 years of age without any morphological findings
Echocardiography
  • Every 1-2 years in subjects < 40 years of age or when indicated**
  • Every 3-5 years or when indicated in subjects > 40 years of age**
CMR
  • First visit
  • Every 1-2 years in subjects < 40 years of age or when indicated**
  • Every 3-5 years or when indicated in subjects > 40 years of age**
CT
Patients who are difficult to assess with echo and unsuitable for CMR

* in patients with CMR incompatible devices
** clinical or ECG changes suggestive of disease progression

Abbreviations:
AC: arrhythmogenic cardiomyopathy
CMR: cardiac magnetic resonance
CT: multidetector computed tomography
ICD: implantable cardioverter defibrillator.