Early pregnancy losses are common amongst healthy women. Current guidelines do not support the routine screening of women with pregnancy loss for inherited thrombophilias. Moreover, there are recommendations against instituting thromboprophylaxis in women with inherited thrombophilias wishing to achieve a successful term pregnancy. By performing testing for inherited thrombophilias patients may be unnecessarily exposed to the harms of thromboprophylaxis, inappropriately labeled with a disease-state, and may unnecessarily modify future plans for travel, pregnancy or surgery based on detection of an "asymptomatic" thrombophilia. Further, patients with negative testing may receive false reassurance.
Conditions: Early Pregnancy Losses, Spontaneous Abortion, Miscarriage
Diagnostic Tests: Thrombophilia Testing, Factor V Leiden, Antithrombin AT III Deficiency, Protein C Deficiency, Protein S Deficiency, Antiphospholipid Syndrome, Lupus Anticoagulant, Anticardiolipin Antibodies
Sources