Table 5. Clinical indications defining high-risk patients as candidates for intensive management
* Four-variable Modification of Diet in Renal Disease (MDRD) equation. † Framingham Risk Score.
Clinical or subclinical cardiovascular disease or Chronic kidney disease (nondiabetic nephropathy, proteinuria < 1 g/d, estimated glomerular filtration rate 20-59 mL/min/1.73 m 2 )* or Estimated 10-year global cardiovascular risk 15% † or Age ≥ 75 years Patients with  1 clinical indications should consent to intensive management