Indications for Drug Therapy for Adults with Hypertension Without Compelling Indications for Specific Agents

1. Antihypertensive therapy should be prescribed for average DBP measurements of 100 mmHg or higher (Grade A), or average SBP measurements of 160 mmHg or higher (Grade A) in patients without macrovascular target organ damage or other cardiovascular risk factors.
2. Antihypertensive therapy should be strongly considered for average DBP readings of 90 mmHg or higher (Grade A) or for average SBP readings of 140 mmHg or higher (Grade B for 140 mmHg to 160 mmHg; Grade A for higher than 160 mmHg) in the presence of macrovascular target organ damage or other independent cardiovascular risk factors.