Practical Tips
Advise patients to stop taking statin therapy and contact the prescribing healthcare provider if worrisome symptoms develop The effort spent persevering with statin therapy in subjects with adverse effects should be directly related to the level of risk for the individual patient In highest-risk patients All options should be exercised before changing to alternate lipid lowering therapy or withdrawing all lipid lowering treatment Lower-dose combination therapy remains an option for these patients Strong emphasis should be put on a more aggressive nonpharmacological approach, such as diet modulation and exercise For lower-risk patients A re-evaluation of the need for lipid lowering therapy should preceded a change to alternative therapy because outcome studies are not robust

Practical Tips

Advise patients to stop taking statin therapy and contact the prescribing healthcare provider if worrisome symptoms develop

The effort spent persevering with statin therapy in subjects with adverse effects should be directly related to the level of risk for the individual patient

In highest-risk patients
- All options should be exercised before changing to alternate lipid lowering therapy or withdrawing all lipid lowering treatment
- Lower-dose combination therapy remains an option for these patients
- Strong emphasis should be put on a more aggressive nonpharmacological approach, such as diet modulation and exercise
For lower-risk patients
- A re-evaluation of the need for lipid lowering therapy should preceded a change to alternative therapy because outcome studies are not robust