Table 27: Diuretic dosing for the treatment of acute heart failure (AHF)
| eGFR: >=60 mL/min/1.73m2 |
|---|
| Patient: New onset HF or no current diuretic therapy |
|
Initial IV dose*: Furosemide 20-40 mg 2-3 times daily Maintenance oral dose: Lowest diuretic dose that allows for clinical stability is the ideal dose |
| Patient: Established HF or chronic oral diuretic therapy |
|
Initial IV dose*: Furosemide dose IV equivalent of oral dose Maintenance oral dose: Lowest diuretic dose that allows for clinical stability is the ideal dose |
| eGFR: <60 mL/min/1.73m2 |
|---|
| Patient: New onset HF or no current diuretic therapy |
|
Initial IV dose*: Furosemide 20-80 mg 2-3 times daily Maintenance oral dose: Lowest diuretic dose that allows for clinical stability is the ideal dose |
| Patient: Established HF or chronic oral diuretic therapy |
|
Initial IV dose*: Furosemide dose IV equivalent of oral dose Maintenance oral dose: Lowest diuretic dose that allows for clinical stability is the ideal dose |
eGFR (estimated glomerular filtration rate) is calculated from the Cockroft-Gault, CKD-EPI or Modification of Diet in Renal Disease formula. See section 7.4.2 for details.
*Intravenous continuous furosemide at doses of 5 to 20mg/h is also an option.
CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration;