Table 2: Risk Scores
Table 2 shows examples of HF prognostic scores which can be easily accessed and calculated, and describes the strengths and limitations of the studies used to develop these scores.
| Score Name: Seattle Heart Failure Model |
|---|
| Population |
| HFrEF |
| Endpoint |
| Mortality risk at 1, 2 and 5 years with or without intervention. Mean life expectancy. |
| Other Considerations |
| Restricted to clinical trial patients with ‘severe’ HF; Lab data entry non-SI units; More than 20 variables to enter. |
| Access |
| https://depts.washington.edu/shfm/ |
| Variables |
| Age, gender, NYHA class, weight, EF, SBP, ischemic etiology, diuretic dose, Na, lymphocyte count, Hgb, cholesterol, uric acid, use of ACEi/ARB/BB/aldosterone blocker/allopurinol/statins, QRS>120msec, use of device therapy |
| Score Name: MAGGIC Risk Score |
|---|
| Population |
| HFrEF and HFpEF |
| Endpoint |
| Mortality risk at 1 and 3 years |
| Other Considerations |
| Cohorts from many sites; missing data in the overall analysis. |
| Access |
| www.heartfailurerisk.org |
| Variables |
| Age, gender, NYHA class, diabetes, COPD, timing of diagnosis, EF, smoking, SBP, creatinine, BMI, use of beta-blocker/ACEi/ARB |
| Score Name: 3C-HF |
|---|
| Population |
| HFrEF and HFpEF |
| Endpoint |
| Mortality risk at 1 year |
| Other Considerations |
| Patients from centres with experience with HF management; mostly Caucasian patients; Lab data entry in non-SI units. |
| Access |
| http://www.3chf.org/site/home.php |
| Variables |
| Age, NYHA class, AF, valvular heart disease, EF, anemia, diabetes, hypertension, creatinine, use of ACEi/ARB or beta-blockers. |
| Score Name: BCN- Bio-HF |
|---|
| Population |
| HFrEF and HFpEF |
| Endpoint |
| Mortality risk at 1,2 and 3 years |
| Other Considerations |
| Limited to patients with chronic HF treated in HF unit in a tertiary hospital. Lab data entry in US units. Use of biomarkers improves accuracy but is optional. |
| Access |
| www.BCNBioHFcalculator.cat |
| Variables |
| Age, gender, NYHA class, Na, eGFR, Hgb, EF, diuretic dose, use of statins, beta-blockers or ACEi/ARB. Optional: hs-cTnT, ST2, Nt-pro-BNP |
| Score Name: EFFECT |
|---|
| Population |
| Hospitalized HFrEF and HFpEF |
| Endpoint |
| 30-day and 1-year mortality |
| Other Considerations |
| Limited to hospitalized patients; missing current clinically important variables |
| Access |
| http://www.ccort.ca/Research/CHFRiskModel.aspx |
| Variables |
| Age, respiratory rate, SBP, BUN, Na, CVD, dementia, COPD, cirrhosis, cancer, Hgb |
| Score Name: EHMRG |
|---|
| Population |
| HFrEF and HFpEF patients presenting to the Emergency Department |
| Endpoint |
| 7 day mortality |
| Other Considerations |
| Limited to patients presenting to the ER and only short-term mortality; missing current clinically important variables |
| Access |
| https://ehmrg.ices.on.ca |
| Variables |
| Age, arrival by ambulance, triage SBP, triage HR, triage O2 sat, potassium, creatinine, active cancer, metolazone, troponin. Optional: BNP |
| Score Name: ELAN |
|---|
| Population |
| Hospitalized HFrEF and HFpEF |
| Endpoint |
| 180-day mortality |
| Other Considerations |
| Limited to hospitalized patients |
| Variables |
| Age, edema, SBP, serum sodium, serum urea, NYHA class at discharge, NT-proBNP at discharge and change in NT-proBNP |
| Score Name: ADHERE |
|---|
| Population |
| HFrEF and HFpEF |
| Endpoint |
| In-hospital mortality |
| Other Considerations |
| Limited to hospitalized patients |
| Variables |
| BUN, creatinine, SBP |
| Score Name: LACE |
|---|
| Population |
| Hospitalized patients |
| Endpoint |
| 30-day mortality or readmission |
| Other Considerations |
| Limited to hospitalized patients |
| Variables |
| Length of stay, acute admission, comorbidity index, # of ED visits in last 6 months |