| Definitions of stroke risk factors |
| Congestive heart failure |
| Documented moderate to severe systolic dysfunction; signs and symptoms of heart failure with reduced ejection fraction; or recent decompensated heart failure that required hospitalization irrespective of ejection fraction |
| Hypertension |
| Resting blood pressure > 140 mm Hg systolic and/or > 90 mm Hg diastolic on at least 2 occasions or current antihypertensive pharmacological treatment |
| Age 65 |
| Age ≥ 65 years |
| Diabetes mellitus |
| Fasting plasma glucose concentration ≥ 7.0 mmol/L (126 mg/dL) or treatment with oral
hypoglycemic agents and/or insulin |
| Stroke/transient ischemic attack/peripheral embolism |
Ischemic stroke: focal neurologic deficit of sudden onset diagnosed by a neurologist, lasting > 24 hours, and caused by ischemia; Transient ischemic attack: focal neurological deficit of sudden onset diagnosed by a neurologist, lasting
< 24 hours; Peripheral embolism: thromboembolism outside the brain, heart, eyes, and lungs, or pulmonary
embolism (defined by the responsible physician) |
| Vascular disease |
| Coronary artery disease, peripheral artery disease, or aortic plaque |