Expert opinion survey regarding the clinical use of a NOAC in relation to the following commonly encountered scenarios: Would you consider NOAC use to be: (1) contraindicated or (2) not contraindicated (ie, reasonable to use) with the following valvular disorders?

NOAC use is contraindicated NOAC use is reasonable
Mechanical heart valves
  • In any position (100% agreement)
 Bioprosthetic heart valve
  • Aortic position (82% agreement)
  • Mitral position (73% agreement)
Rheumatic mitral stenosis
  • Mild (47% agreement)
  • Moderate-severe (88% agreement)
  • After commissurotomy (42% agreement)
 Mitral annuloplasty
  • With or without prosthetic ring (88% agreement)
Non-rheumatic mitral stenosis
  • Moderate or severe (69% agreement)
 Non-rheumatic mitral stenosis
  • Mild (97% agreement)
Mitral regurgitation
  • Mild (97% agreement)
  • Moderate-severe (>90% agreement)
Tricuspid regurgitation
  • Any severity (98% agreement)
Aortic stenosis or regurgitation
  • Mild (98% agreement)
  • Moderate to severe (80% agreement)

NOAC, novel non-vitamin K antagonist.