| Favours rate control | Favours rhythm control |
| Persistent AF | Paroxysmal AF Newly detected AF |
| Less symptomatic | More symptomatic |
| Aged ≥65 years | Aged <65 years |
| Hypertension | No hypertension |
| No history of congestive heart failure | Congestive heart failure clearly exacerbated by AF |
| Previous antiarrhythmic drug failure | No previous antiarrhythmic drug failure |
| Patient preference | Patient preference |