Favours rate controlFavours rhythm control
Persistent AFParoxysmal AF
Newly detected AF
Less symptomaticMore symptomatic
Aged ≥65 yearsAged <65 years
HypertensionNo hypertension
No history of congestive heart failureCongestive heart failure clearly exacerbated by AF
Previous antiarrhythmic drug failureNo previous antiarrhythmic drug failure
Patient preferencePatient preference