We recommend that patients who have a contraindication to β-blocker therapy before or after cardiac surgery be considered for prophylactic therapy with amiodarone to prevent postoperative AF. (Recommendation Strong, Quality High)
Values and preferences: This recommendation places a high value on minimizing the patient population exposed to the potential adverse effects of amiodarone and a lower value on data suggesting that amiodarone is more effective than β-blockers for this purpose.