Strength of a Recommendation
Strong:Benefits do (or do not) outweigh risks and burdens
Conditional:Benefits and risks are finely balanced, or appreciable uncertainty exists about the magnitude of benefits and risks. Additionally, fully informed patients are liable to make different choices.
Quality of Evidence
High:Further research is very unlikely to change our confidence in the estimate of effect.
Moderate:Futher research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
Low:Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
Very Low:Any estimate is very uncertain.