Recommendation 35. We suggest an initial regimen of ASA 81 mg daily plus clopidogrel 75 mg daily with either parenteral or OAC (in accordance with DVT/PE recommendations). ASA may be discontinued as early as the day after PCI or it can be continued up to 6 months of treatment, depending on the risk of recurrent ischemic events vs major bleeding. After ASA discontinuation, we suggest that OAC plus clopidogrel 75 mg daily be continued for up to 12 months after the initial PCI (Weak Recommendation; Very Low-Quality Evidence).
Recommendation 36. For patients requiring an elective PCI, we recommend delaying PCI if appropriate until the completion of parenteral or OAC for VTE (Strong Recommendation; Very Low-Quality Evidence).
Values and preferences. This recommendation places emphasis on optimizing the prevention and treatment of DVT and PE with either a parenteral or oral anticoagulant.