1. LV global longitudinal diastolic strain rate measurements during the isovolumic relaxation period and during early diastole by STE have a significant association with the time constant of LV relaxation (τ). These parameters have been used in conjunction with mitral E velocity to estimate LV filling pressures and to predict outcome in several disease states.
2. The timing of peak untwisting rate can be of value in diagnosing patients with diastolic dysfunction and normal LV volumes and EF. In the latter group of patients, delayed peak of LV untwisting rate is often present.
3. An inverse correlation is present between LA systolic strain and mean wedge pressure. Although promising, there are technical limitations, and experience is essential.